The Fake Clinical Trials of Dr. Scott Reuben
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By now, we’ve all heard something or other about Dr. Scott Reuben, the well respected and highly influential clinical researcher who, as it turns out, fabricated the data used in a full twenty one drug studies published in peer-reviewed medical journals.
The studies, for which Reuben was handsomely paid by the drug companies, promoted the safety and efficacy of drugs like Pfizer’s Bextra, Merck’s Vioxx, Lyrica, Celebrex and Effexor—many of which have since proved dangerous (and even fatal), and some of which have been pulled from the market.
NaturalNews.com recently published a complete listing of the studies Reuben fabricated. Reading through it is absolutely maddening. Now that peer-reviewed medical journals are out, what sources can we truly trust for valid information about prescription drugs?
Medical studies authored / fabricated by the shamed Dr. Scott Reuben
Preventing the development of chronic pain after thoracic surgery.
Reuben SS, Yalavarthy L.
J Cardiothorac Vasc Anesth. 2008 Dec;22(6):890-903. Epub 2008 May 7. No abstract available.
PMID: 18834790
A prospective randomized trial on the role of perioperative celecoxib administration for total knee arthroplasty: improving clinical outcomes.
Reuben SS, Buvenandran A, Katz B, Kroin JS.
Anesth Analg. 2008 Apr;106(4):1258-64, table of contents.
PMID: 18349203
Update on the role of nonsteroidal anti-inflammatory drugs and coxibs in the management of acute pain.
Reuben SS.
Curr Opin Anaesthesiol. 2007 Oct;20(5):440-50. Review.
PMID: 17873597
The effect of initiating a preventive multimodal analgesic regimen on long-term patient outcomes for outpatient anterior cruciate ligament reconstruction surgery.
Reuben SS, Ekman EF.
Anesth Analg. 2007 Jul;105(1):228-32.
PMID: 17578979
Evaluating the analgesic efficacy of administering celecoxib as a component of multimodal analgesia for outpatient anterior cruciate ligament reconstruction surgery.
Reuben SS, Ekman EF, Charron D.
Anesth Analg. 2007 Jul;105(1):222-7.
PMID: 17578978
Preventing the development of chronic pain after orthopaedic surgery with preventive multimodal analgesic techniques.
Reuben SS, Buvanendran A.
J Bone Joint Surg Am. 2007 Jun;89(6):1343-58. Review.
PMID: 17545440
The efficacy of postoperative perineural infusion of bupivacaine and clonidine after lower extremity amputation in preventing phantom limb and stump pain.
Madabhushi L, Reuben SS, Steinberg RB, Adesioye J.
J Clin Anesth. 2007 May;19(3):226-9.
PMID: 17531734
Chronic pain after surgery: what can we do to prevent it.
Reuben SS.
Curr Pain Headache Rep. 2007 Feb;11(1):5-13. Review.
PMID: 17214915
The analgesic efficacy of celecoxib, pregabalin, and their combination for spinal fusion surgery.
Reuben SS, Buvanendran A, Kroin JS, Raghunathan K.
Anesth Analg. 2006 Nov;103(5):1271-7.
PMID: 17056968
Acute post-surgical pain management: a critical appraisal of current practice, December 2-4, 2005.
Rathmell JP, Wu CL, Sinatra RS, Ballantyne JC, Ginsberg B, Gordon DB, Liu SS, Perkins FM, Reuben SS, Rosenquist RW, Viscusi ER.
Reg Anesth Pain Med. 2006 Jul-Aug;31(4 Suppl 1):1-42.
PMID: 16849098
Postoperative modulation of central nervous system prostaglandin E2 by cyclooxygenase inhibitors after vascular surgery.
Reuben SS, Buvanendran A, Kroin JS, Steinberg RB.
Anesthesiology. 2006 Mar;104(3):411-6.
PMID: 16508386
The incidence of complex regional pain syndrome after fasciectomy for Dupuytren's contracture: a prospective observational study of four anesthetic techniques.
Reuben SS, Pristas R, Dixon D, Faruqi S, Madabhushi L, Wenner S.
Anesth Analg. 2006 Feb;102(2):499-503.
PMID: 16428550
The effect of cyclooxygenase-2 inhibition on acute and chronic donor-site pain after spinal-fusion surgery.
Reuben SS, Ekman EF, Raghunathan K, Steinberg RB, Blinder JL, Adesioye J.
Reg Anesth Pain Med. 2006 Jan-Feb;31(1):6-13.
PMID: 16418018
Interscalene block superior to general anesthesia.
Reuben SS.
Anesthesiology. 2006 Jan;104(1):207; author reply 208-9. No abstract available.
PMID: 16394719
High dose nonsteroidal anti-inflammatory drugs compromise spinal fusion.
Reuben SS, Ablett D, Kaye R.
Can J Anaesth. 2005 May;52(5):506-12.
PMID: 15872130
More on current issues in pain management for the primary care practitioner. Acute pain: a multi-modal management approach.
Carr DB, Reuben S.
J Pain Palliat Care Pharmacother. 2005;19(1):69-70. No abstract available.
PMID: 15814519
The effect of cyclooxygenase-2 inhibition on analgesia and spinal fusion.
Reuben SS, Ekman EF.
J Bone Joint Surg Am. 2005 Mar;87(3):536-42.
PMID: 15741619
The prevention of post-surgical neuralgia.
Reuben SS.
Pain. 2005 Jan;113(1-2):242-3; author reply 243-4. No abstract available.
PMID: 15621388
Surgery on the affected upper extremity of patients with a history of complex regional pain syndrome: the use of intravenous regional anesthesia with clonidine.
Reuben SS, Rosenthal EA, Steinberg RB, Faruqi S, Kilaru PA.
J Clin Anesth. 2004 Nov;16(7):517-22.
PMID: 15590255
Preventing the development of complex regional pain syndrome after surgery.
Reuben SS.
Anesthesiology. 2004 Nov;101(5):1215-24. Review. No abstract available.
PMID: 15505459
Evaluation of efficacy of the perioperative administration of venlafaxine XR in the prevention of postmastectomy pain syndrome.
Reuben SS, Makari-Judson G, Lurie SD.
J Pain Symptom Manage. 2004 Feb;27(2):133-9.
PMID: 15157037
Analgesic effect of clonidine added to bupivacaine 0.125% in paediatric caudal blockade.
Joshi W, Connelly NR, Freeman K, Reuben SS.
Paediatr Anaesth. 2004 Jun;14(6):483-6.
PMID: 15153211
The perioperative use of cyclooxygenase-2 selective nonsteroidal antiinflammatory drugs may offer a safer alternative.
Reuben SS, Connelly NR.
Anesthesiology. 2004 Mar;100(3):748. No abstract available.
PMID: 15109000
An evaluation of the safety and efficacy of administering rofecoxib for postoperative pain management.
Joshi W, Connelly NR, Reuben SS, Wolckenhaar M, Thakkar N.
Anesth Analg. 2003 Jul;97(1):35-8, table of contents.
PMID: 12818939
An evaluation of the analgesic efficacy of intravenous regional anesthesia with lidocaine and ketorolac using a forearm versus upper arm tourniquet.
Reuben SS, Steinberg RB, Maciolek H, Manikantan P.
Anesth Analg. 2002 Aug;95(2):457-60, table of contents.
PMID: 12145071
Preoperative administration of controlled-release oxycodone for the management of pain after ambulatory laparoscopic tubal ligation surgery.
Reuben SS, Steinberg RB, Maciolek H, Joshi W.
J Clin Anesth. 2002 May;14(3):223-7.
PMID: 12031758
Intravenous regional anesthesia with clonidine in the management of complex regional pain syndrome of the knee.
Reuben SS, Sklar J.
J Clin Anesth. 2002 Mar;14(2):87-91.
PMID: 11943518
Preemptive multimodal analgesia for anterior cruciate ligament surgery.
Reuben SS, Sklar J.
Reg Anesth Pain Med. 2002 Mar-Apr;27(2):225; author reply 225-6. No abstract available.
PMID: 11915075
Evaluation of the safety and efficacy of the perioperative administration of rofecoxib for total knee arthroplasty.
Reuben SS, Fingeroth R, Krushell R, Maciolek H.
J Arthroplasty. 2002 Jan;17(1):26-31.
PMID: 11805921
The preemptive analgesic effect of rofecoxib after ambulatory arthroscopic knee surgery.
Reuben SS, Bhopatkar S, Maciolek H, Joshi W, Sklar J.
Anesth Analg. 2002 Jan;94(1):55-9, table of contents.
PMID: 11772800
